GSES2

7TMSP

xUMFs of G Protein-Coupled Receptors (GPCRs)

calculated for 200 a.a. TM bundles
(of receptors with available inactive- and active- states)

GeneUniProtEntriesChainsLength(%)ResolutionUMF
ADORA2AP29274484848.52.5263.6
ADRB1P07700202041.42.8168.8
ADRB2P07550292948.43.0561.7
CHRM2P081726642.92.9983.1
CNR1P215545542.42.8852.5
EDNRBP245307745.22.6766.2
Ntsr1P2078981047.22.9969.2
OPRD1P411434753.82.7773.3
OPRK1P411453652.63.164.9
RHOP02699353557.52.9349.3

200 a.a. 7TM helices of class A GPCRs are assigned as follows
(Ballesteros & Weinstein numbering

1.35 - 1.59 (25 residues)
2.38 - 2.67 (30 residues)
3.22 - 3.55 (34 residues)
4.39 - 4.63 (25 residues)
5.36 - 5.65 (30 residues)
6.29 - 6.60 (32 residues)
7.32 - 7.55 (24 residues)

GPCRs of known structures

Rhodopsin family

Others